It is one of the great mysteries of the coronavirus: knowing why people with the virus do not develop any symptoms. Researchers at Aarhus University Hospital in Denmark found that it results from the virus being able to hide its genome so that it is not recognized.
The answer lies in the so-called “alveolar macrophages” [um tipo de glóbulo branco na superfície dos alvéolos, são um mecanismo de defesa dos pulmões] which determine how quickly immunity to a coronavirus infection can be produced.
These macrophages can be the first to encounter the virus during an infection, their reaction has a profound impact on the outcome of the infection. The discovery was published in the journal EMBO Reports.
The results suggest that the coronavirus can hide its genetic material in a way that is not recognized in alveolar macrophages.
The detection of asymptomatic patients is a key factor for the spread of the virus, however it is also important to control the transmission of those patients who have overcome the disease but are still carriers of the virus
A study by Polliclinico Universitario Fondazione Agostino Gemelli in Rome (Italy) reported that about 17% of patients who were considered to have fully recovered from Covid-19 had positive results for the virus in follow-up tests.