It is the first known case of a newborn baby in which IgG antibodies were detected, one of the five antibodies that the organism produces as a way of defending pathogens associated with the SARS-CoV-2 virus, advances the Spanish newspaper “La Vanguardia” . This happened after the mother was vaccinated against COVID-19 three weeks before the baby was born.
The mother is a health professional and was 36 weeks and three days pregnant when she was submitted to the first dose of Moderna’s drug. And it seems that it was enough time and dose for the IgG antibodies – which act against the SARS-CoV-2 protein S, a protein that the coronavirus uses to enter human cells – to enter the baby’s bloodstream, once they were detected in Umbilical cord blood.
“We showed that the IgG SARS-CoV-2 antibodies are detectable in the umbilical cord blood sample of a newborn after a single dose of the vaccine,” explains the team of North American researchers from Florida Atlantic University who identified and studied the case. After the discovery, scientists argue that there is an urgent need to “investigate the safety and efficacy of vaccination against SARS-CoV-2 during pregnancy”.
The preliminary study published in medRxiv (a repository of scientific articles), still does not have precise conclusions as to the immunity of the vaccine against COVID-19 in newborns and the ideal moment for the maternal vaccination, but it is known that the maternal vaccination against influenza and TDaP have been successful in protecting the newborn by transmitting antibodies through the placenta. Therefore, the same would be expected of the vaccine against COVID-19, say the scientists.
However, the mother has already received the second dose of the vaccine, thus complying with the 28-day vaccination protocol recommended for Moderna’s drug.